diff --git a/src/transformers/quantizers/quantizer_mxfp4.py b/src/transformers/quantizers/quantizer_mxfp4.py
index 061ca072f0..b3e52e5e1c 100644
--- a/src/transformers/quantizers/quantizer_mxfp4.py
+++ b/src/transformers/quantizers/quantizer_mxfp4.py
@@ -56,15 +56,16 @@ class Mxfp4HfQuantizer(HfQuantizer):
                 "Using mxfp4 quantization requires torch"
                 "Please install the latest version of torch ( pip install --upgrade torch )"
             )
+
+        if self.quantization_config.dequantize:
+            return
+
         if not torch.cuda.is_available():
             raise RuntimeError("Using MXFP4 quantized models requires a GPU")
 
         if not is_accelerate_available():
             raise ImportError("Using mxfp4 requires Accelerate: `pip install accelerate`")
 
-        if self.quantization_config.dequantize:
-            return
-
         compute_capability = torch.cuda.get_device_capability()
         major, minor = compute_capability
 
diff --git a/tests/quantization/mxfp4/test_mxfp4.py b/tests/quantization/mxfp4/test_mxfp4.py
index 2194c2d321..56268b44df 100644
--- a/tests/quantization/mxfp4/test_mxfp4.py
+++ b/tests/quantization/mxfp4/test_mxfp4.py
@@ -131,6 +131,52 @@ class Mxfp4QuantizerTest(unittest.TestCase):
                 if "compute capability" in str(e):
                     self.fail("Should not raise compute capability error when dequantize=True")
 
+    def test_quantizer_validation_dequantize_on_cpu(self):
+        """Test quantizer validation with dequantize enabled on CPU-only environment"""
+        with patch("torch.cuda.is_available", return_value=False):
+            from transformers.quantizers.quantizer_mxfp4 import Mxfp4HfQuantizer
+
+            config = Mxfp4Config(dequantize=True)
+            quantizer = Mxfp4HfQuantizer(config)
+
+            # Should not raise error when dequantize=True even without CUDA
+            try:
+                quantizer.validate_environment()
+            except RuntimeError as e:
+                if "requires a GPU" in str(e):
+                    self.fail("Should not raise GPU requirement error when dequantize=True on CPU")
+
+    def test_quantizer_validation_order_dequantize_before_cuda_check(self):
+        """Test that dequantize check happens before CUDA availability check"""
+        # Mock both torch.cuda.is_available and is_accelerate_available to return False
+        with (
+            patch("torch.cuda.is_available", return_value=False),
+            patch(
+                "transformers.quantizers.quantizer_mxfp4.is_accelerate_available",
+                return_value=False,
+            ),
+        ):
+            from transformers.quantizers.quantizer_mxfp4 import Mxfp4HfQuantizer
+
+            # Test with dequantize=True - should pass even without CUDA and accelerate
+            config = Mxfp4Config(dequantize=True)
+            quantizer = Mxfp4HfQuantizer(config)
+
+            # This should not raise any error because dequantize check comes first
+            try:
+                quantizer.validate_environment()
+            except (RuntimeError, ImportError) as e:
+                if "requires a GPU" in str(e) or "requires Accelerate" in str(e):
+                    self.fail(f"Should not raise error when dequantize=True: {e}")
+
+            # Test with dequantize=False - should still fail due to missing CUDA
+            config = Mxfp4Config(dequantize=False)
+            quantizer = Mxfp4HfQuantizer(config)
+
+            with self.assertRaises(RuntimeError) as context:
+                quantizer.validate_environment()
+            self.assertIn("requires a GPU", str(context.exception))
+
     def test_quantizer_validation_missing_triton(self):
         """Test quantizer validation when triton is not available"""
         with (